To achieve best casino real money app’s basic management philosophy, we must operate the company based on a long-term perspective in terms of both solving challenges of society through our business activities and engaging in activities consistent with being a responsible member of society. Such corporate management is only possible if we first gain the trust of our various stakeholders, including customers, shareholders, business partners, employees, and local communities.
To build a relationship of trust with stakeholders, we will actively engage in smooth, two-way communication with them regarding all aspects of our corporate activities. Doing so is not only our corporate responsibility, but is also essential in terms of enhancing corporate value.
|Customers||Offer products and services that solve challenges of customers and society||
|Shareholders||To promote better understanding of management policies and increase corporate value, disclose appropriate information whenever appropriate and engage in dialog with shareholders.||
|To implement corporate social responsibilities throughout the entire supply chain, cooperate with suppliers to ensure human rights are respected and environmental impacts are minimized.||
|Employees||Respect employee diversity, train human resources, and strive to provide a safe and comfortable working environment.||
|We are also actively involved in solving society problems in communities where a best casino real money app office or Group company is located, or in society challenges related to business activities||
Due to the mountain of society challenges in the healthcare eld, there is great anticipation for revolutionary innovations. Therefore, we invited Dr. Hisataka Kobayashi, Senior Investigator at the National Cancer Institute (NCI) in the United States, who developed a cancer photoimmunotherapy method that kills cancer cells by irradiation with near-infrared light, to discuss the innovation and the role of best casino real money app technology in treating cancer. The following is from a conversation between Dr. Hisataka Kobayashi and Takashi Marume, General Manager of the Healthcare Business Strategy Unit in best casino real money app's Corporate Strategy Planning Department.,rummy passion
|Date||May 15, 2018|
|Location||best casino real money app Corporation, Sanjo Works|
Marume: Currently we are in the second year of best casino real money app Corporation's 3-year medium-term management plan. Originally, the previous medium-term management plan was based on solving challenges faced by customers, but the current plan is based on solving challenges faced by both customers and society in general.
Based on that focus, the plan specifies four important growth fields. One of those fields is healthcare. best casino real money app intends to create additional value by combining X-ray image processing technology, which is your expertise, with mass spectrometry technology, which is one of the core technologies of best casino real money app, and then use it to offer comprehensive healthcare support for everything from routine health management to nursing care. best casino real money app refers to this field as "advanced healthcare." Therefore, beginning last year, best casino real money app has been busy starting various research, development, service, and new businesses in the advanced healthcare field. Today, we hope to hear various ideas and comments you may have about such applications
free slots 777 games,Marume: Could you provide a simple explanation of photoimmunotherapy for cancer?
Dr. Kobayashi: Photoimmunotherapy is a technique for reducing the number of cancer cells and actively increasing the body's immunity against cancer. In other words, the basic concept of the treatment is to reduce enemy forces and strengthen friendly forces. Therefore, in order to destroy only cancer cells without damaging normal cells, we devised a technique for attaching chemical substances to antibodies that specifically target cancer cells and then activating the antibodies with light. We also modified the method used to destroy the cancer cells. Using conventional methods of destroying cells with drugs takes time, mummifies the cells, and does not stimulate the immune system. In contrast, if cells are physically destroyed within the body, the cell debris stimulates the immune system. If the debris is something that was not previously recognized in the body, it not only increases the variety of immunity, but also serves as a key to starting new immunity.,cricket id app
rummy passion,Marume: Did that idea occur to you suddenly one day? What was the thinking process that resulted in the concept?
Dr. Kobayashi: I used to be involved in treating cancer patients with radiotherapy and even wrote research papers on radiotherapy. At the time, radiodiagnostics and radiotherapy were performed within the same department and we were trying to find ways to combine them. Later, when I became a researcher, I decided to create a treatment method that only killed cancer cells, to extent possible. That resulted in trying to create a method that did not simply kill cancer cells, but that also created systems within the body that would enable a full recovery. Therefore, I ended up successively trying various combinations in an effort to identify methods that destroyed cancer cells as successfully as possible and destroyed them in a manner different than by conventionally using drugs, so that other systems in the body could also be utilized.,estar online game
footballs,Marume: Once the concept occurred to you, what did you do next to realize the system? Please explain the "how to" portion of that process.
free bet calculator,Dr. Kobayashi: I thought of using antibodies that are specifically attracted to cancer cells. I had previously been involved in researching the behavior of antibodies, so I was very familiar with how different sizes of antibodies behaved.
Marume: How much basic research did you do?,football yesterday
Dr. Kobayashi: I became involved in studying antibodies in 1984, when I started taking pathology classes in my fourth year at university. Given the high specificity of antibodies, I wondered how that characteristic could be used to transport something to cancer cells to treat the cancer.
When I returned to Kyoto University for graduate school, my work involved researching methods for killing cancer cells by attaching radioisotopes to antibodies for delivery to the cancer cells. My doctoral dissertation was about how to improve such methods. Next, given that normal cells are irradiated when radiation enters the body, I wrote a thesis about how to generate antibodies as quickly as possible, and more specifically, how to generate radioisotopes as quickly as possible. However, it is difficult to control antibodies before they reach the cancer, because they must flow through the blood.
I continued that research at the NIH (National Institutes of Health), however the conclusion eventually reached from the research at NIH and other joint research was that injections of a toxic substance will always affect normal organs. Therefore, I realized the injected substance needs to be non-toxic, but controlled so that it becomes toxic, so now I am researching methods for switching the toxicity ON/OFF
baseball facts,Marume: So it wasn't a sudden realization, but rather a logical accumulation of many elements.
Dr. Kobayashi: Consequently, it has continued for 34 year.Initially, I focused on how the chemical substances interacted, but eventually aborted that approach because it meant both the first and second agents are chemical substances and so the treatment would require obtaining approval for two drugs, which would be a major undertaking, and because of the presumed quantitative limits on how much of a foreign substance could be introduced in the body.
In that case, I thought, if the first agent is a drug, then the second agent should be some sort of physical energy, so I started searching for a suitable physical energy. That resulted in concluding that near-infrared light offered the most potential.
The next step involved searching for a chemical substance that could be switched ON/OFF with light energy from the absorption of near-infrared light. That process led us to the drug we are currently using, which enabled the system for delivering the drug by antibodies.
opera chips,Marume: I see. So, the purpose for the drug was determined first and then you searched for the drug to fit that purpose? It must have taken a long time to search through all the possible combinations and drugs before reaching a successful solution. What was it that kept your motivation level up through that process?
Dr. Kobayashi: The biggest factor was that I love research. I was also motivated by a strong desire to help cure patients. In other words, I think my desire to leave something from my medical research that would help patients, even a little, was a significant motivation.,10bet ghana
Marume: Given that best casino real money app Corporation also has specified a management principle of "Realizing Our Wishes for the Well-being of both Mankind and the Earth," we share a similar motivation to help save patients through healthcare and medical technology.
Next, could you summarize some of the ways best casino real money app has been involved during that process of developing your photoimmunotherapy method?
Dr. Kobayashi: It began when Mr. Hattori was President. When I talked about how the use of light potentially could be expanded into medical treatment applications, not just imaging, President Hattori showed strong interest.
Since then, I have obtained help from best casino real money app in various situations that required the help of professionals, such as to analyze polymers.
free roulette games to play now,Marume: What is the current status and future plans for the research? I understand the method is currently in clinical trials, but how much longer will those trials take to complete?
funbett,Dr. Kobayashi: In the United States, we finished phase 2 and are currently in phase 3, so it won't take that much longer. In Japan as well, trials have started at the National Cancer Center Hospital East, which should be completed quickly, provided the first trial is successful.
Marume: Does that mean that, if all goes well, it might be released soon? Will you expand its scope to include other types of cancer, for example?,fortune 88 slots online
boylesports casino,Dr. Kobayashi: In terms of expanding the scope using the same type of antibody, yes, of course we are planning to expand the scope. Severe breast cancers and other conditions that are currently not adequately treated using anticancer agents should also provide good targets.
fallout 76 mr greene,Marume: It seems the method offers only benefits for the patient, such as no pain, no adverse effects, quick efficacy, and improved immunity.
1/2 soccer bet,Marume: How can best casino real money app help with your research in the future? What are your expectations?
sports dafa,Dr. Kobayashi: We would appreciate help with clinical trials, of course. For example, I would be especially grateful for help with using a LIGHTVISION imaging system (see note) to image the high specificity of antibodies targeting cancer cells. Furthermore, the LIGHTVISION system also shows the attenuation and disappearance of fluorescent light, which can be used as evidence that chemical reactions occurred. I think that objective understanding would help ensure the likelihood of success, for both the patient and physician. It would also be extremely helpful to have an opportunity to make a commitment at the clinical imaging stage, such as by using a mass spectrometer to measure substances in the urine or check for biomarkers, for example, after treatment.
Marume: Do you have any opinions or advice regarding best casino real money app's measures to integrate analytical and medical technologies, as I mentioned earlier regarding the advanced healthcare field, to develop and release technologies for not only medical applications, but also for health management?,soccer live cz
casino money,Dr. Kobayashi: I think integrating such technologies will generate new information not previously available. If physicians need to treat a patient, they will appreciate having more information. For example, it would be great if there was a system that could tell the physician which antibiotics will be most effective for each patient, based on checking for biomarkers before starting a treatment.
Marume: Do you mean individualized medicine or patient-customized treatment?,betway odds
Dr. Kobayashi: Yes, exactly. Patients would be much easier to treat if we could determine their immune system status in advance. In other words, if biomarkers could be used to perform a diagnosis before surgery, based on both immunological and tumor data, physicians could provide better treatments.
To avoid overwhelming physicians with information, it would be even better if only selected data was provided immediately to physicians when they are treating patients. The biggest problem is that the amount of available data has been increasing so much that it is difficult to determine which information is useful.
cash bandits 3 free play,Marume: Do you mean an AI-based system that can select important data from large amounts of collected data and interpret the data?
blackjack google,Dr. Kobayashi: It would be great to have a system that could extract from large amounts of data just the information of interest to the physician and then quickly deliver it to the location where the physician is providing treatment.
Marume: Is delivering it quickly to the treatment location the key point?,kabaddi raider
Dr. Kobayashi: I think the fact that I spent a lot of time on-site where patients are being treated was probably a major factor that resulted in developing my treatment method. There are many things that can only be learned from being on-site, such as identifying the true problems and what things are necessary in reality. I recommend gathering lots of feedback and opinions from those actually using the products.,1/2 soccer bet
bet365 poker bonus code,Marume: That applies to all of best casino real money app's measures, not just advanced healthcare, doesn't it?
soccer live cz,Dr. Kobayashi: Healthcare is a very big field, so if you can successfully identify things that are truly necessary, I think people working in healthcare will be extremely grateful.
Marume: After all, working with a wide variety of people to solve their problems and being useful to society and individuals is what best casino real money app's corporate philosophy is all about, so we look forward to spending time on-site where best casino real money app products are used.,live cricket
For the first time since the last visits in the autumn of 2011 and spring of 2012, I came to the "best casino real money app Corporation Forest" in Nantan City, Kyoto, and was greatly impressed with its transformation and beauty. Thanks to tree thinning, the artificial forest of Japanese cypresses has improved, with better space for airflow, bringing in sufficient sunlight. What concerned me slightly, though, were the natural forests such as Prunus grayana, which are distributed over the lower stretches of the water catchment area.
This was because, in contrast to the upper-layer trees covering the top, there were no lower-layer trees, which there should have been in the middle or lower layer of the forest.
Having said that, seeing youngsters practicing a rugby club in SHIMADZU drill so vigorously that their voices sounded as if trees were falling, I had a feeling that I can rely on future generations to take care of the forest.
The best part of this forest is that you can spend an enjoyable time there with your family.
Honorary Curator of the Kyoto Prefectural Botanical Garden
Guest Professor at Kyoto Prefectural University
tennis opening,We invited some influential individuals to have a dialog about best casino real money app's Environmental and Social Report and best casino real money app's activities in general. The following is a selection from the valuable views expressed during that dialog.
|Date||April 24, 2015|
|Location||best casino real money app Corporation, Sanjo Works|
|Overview||After touring the production plant facility, the product showroom, and so on, they exchanged views with|
Comments from an Outside Expert (1),free roulette games to play now
Deputy Dean, Professor,
Faculty of Safety Science,
I was impressed with best casino real money app's stance on creating products with high added value while striving to satisfy the needs of customers. The report conveys the sincerity and earnestness of Shimadzu. I think the report is wonderful just as it is, but I think corporate value could be further improved by giving more detailed information about company activities to give a better impression, such as regarding corporate social responsibility. That would simultaneously help increase employee motivation and also be important in terms of compliance.
For example, best casino real money app pioneered using control self-assessment practices for risk management. You were also a leader in adopting business continuity planning, corporate governance, and information security practices. I think information about such measures should be included as well. Lately, such information is also important to investors, so I hope the report will indicate that such measures are escalated each year as improvements are made going through PDCA cycles.
Comments from an Outside Expert (2),caesars online slots
Faculty of Law,
Osaka University of Economics and Law
I think the report put more focus on social aspects than the one in 2012 when I participated in your stakeholder dialogue. However, diversified stakeholders have been engaging in evaluation of business activities lately, so it is ever more important for business to provide transparency. In order not to lead to misunderstanding among stakeholders that a lack of information means a lack of activity, information of activities should be proactively disclosed.
Apparently, best casino real money app has developed internal systems such as work-life balance programs and diverse employment for foreigners, so one of pillars for the next report should be "diversity in the workplace", which would shows best casino real money app's policy to be a better place to work for a wider variety of people. I believe that it send a strong message to those interested in working at best casino real money app and also to your current employees.
As the next step, I hope that best casino real money app will establish and implement "social" management systems in addition to environmental ones (EMS), and that you will describe how best casino real money app activities and products are involved in helping people around the world achieve their environmental and health rights.
soccerway j2,Response to Views from Outside best casino real money app
We want to sincerely thank Professor Takano and Associate Professor Sugawara for generously taking time from their busy schedules to come to best casino real money app and offer their valuable insights.The information they provided about current topics and world trends in their respective elds of expertise was extremely stimulating to relevant personnel at Shimadzu. It has provided an invaluable opportunity to renew our awareness of certain issues, such as issues that we need to buckle down and improve further in the future and the importance of including information that would be effective in increasing best casino real money app's corporate value.
best casino real money app remains committed to merging scientic technologies available to best casino real money app with environmental and social measures to contribute to society through our business activities.
Senior Corporate Executive Of cer and Director of best casino real money app Corporation